Review:

Topoisomerase

overall review score: 4.5
score is between 0 and 5
Topoisomerase is a family of enzymes that regulate the overwinding or underwinding of DNA during crucial cellular processes such as DNA replication, transcription, and repair.

Key Features

  • Regulation of DNA topology
  • Prevention of DNA tangling
  • Facilitation of DNA strand breakage and rejoining

Pros

  • Essential for various cellular processes
  • Helps in maintaining genomic stability
  • Target for anticancer drugs

Cons

  • Can be targeted by pathogens to disrupt cellular functions

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Last updated: Sun, Mar 22, 2026, 12:58:59 PM UTC