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Review:

Size Exclusion Chromatography

overall review score: 4.5
score is between 0 and 5
Size-exclusion chromatography is a chromatographic technique used for separating molecules based on their size.

Key Features

  • Separation based on molecule size
  • Column packed with porous material
  • Mobile phase flows through the column by gravity or pressure

Pros

  • Effective in separating molecules based on size
  • Simple and quick method for analysis
  • Non-destructive to samples

Cons

  • Limited resolution for very similar-sized molecules
  • Not suitable for separating very small molecules

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Last updated: Sun, Mar 22, 2026, 09:58:34 AM UTC