Review:
Alternative Splicing
overall review score: 4.5
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score is between 0 and 5
Alternative splicing is a mechanism by which different combinations of exons in a pre-mRNA can be spliced together to generate multiple mRNA transcripts from a single gene.
Key Features
- Diverse transcript variants
- Regulation of gene expression
- Protein diversity
- Tissue-specific expression
Pros
- Increases protein diversity
- Allows for tissue-specific gene expression
- Regulation of gene expression
Cons
- Can lead to aberrant splicing events
- Difficult to predict and study in some cases